BDBM50647288 CHEMBL5597403

SMILES C=CC(=O)Nc1cc2c(Oc3ccc(NC(=O)NCCc4ccc(F)cc4)cc3F)ncnc2cc1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50647288   

TargetEpidermal growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647288(CHEMBL5597403)
Affinity DataIC50: 65nMAssay Description:Inhibition of wildtype EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647288(CHEMBL5597403)
Affinity DataIC50: 305nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed