BDBM50647393 CHEMBL4752870

SMILES O=c1[nH]ncc(N2CCc3c(ncnc3Oc3ccc(F)cc3C(F)(F)F)C2)c1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50647393   

TargetShort transient receptor potential channel 5(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50647393(CHEMBL4752870)
Affinity DataIC50: 8nMAssay Description:Inhibition of TRPC5 (unknown origin) expressed in HEK293 cells assessed as reduction in englerin A stimulated Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetShort transient receptor potential channel 4(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50647393(CHEMBL4752870)
Affinity DataIC50: 18nMAssay Description:Inhibition of TRPC4 (unknown origin) expressed in HEK293 cells assessed as reduction in englerin A stimulated Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetShort transient receptor potential channel 3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50647393(CHEMBL4752870)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TRPC3 (unknown origin) expressed in HEK293 cells assessed as reduction in OAG stimulated Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetShort transient receptor potential channel 6(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50647393(CHEMBL4752870)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TRPC6 (unknown origin) expressed in HEK293 cells assessed as reduction in OAG stimulated Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetShort transient receptor potential channel 7(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50647393(CHEMBL4752870)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TRPC7 (unknown origin) expressed in HEK293 cells assessed as reduction in OAG stimulated Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed