BDBM50647413 CHEMBL5597560

SMILES O=C(CCCCCN1C(=O)[C@@H]2CCCN2Cc2ccccc21)NO

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50647413   

TargetHistone deacetylase 6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50647413(CHEMBL5597560)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of recombinant human full length HDAC6 using Boc-Lys (Ac)-AMC as substrate incubated for 120 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50647413(CHEMBL5597560)
Affinity DataIC50: 437nMAssay Description:Inhibition of C-terminal His6/Flag-tagged recombinant human full length HDAC1 using Boc-Lys (Ac)-AMC as substrate incubated for 120 mins by fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50647413(CHEMBL5597560)
Affinity DataIC50: 499nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys (Ac)-AMC as substrate incubated for 120 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50647413(CHEMBL5597560)
Affinity DataIC50: 731nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human HDAC7 (518 to end residues) expressed in baculovirus expression system using Boc-Lys (Tfa)-AMC ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50647413(CHEMBL5597560)
Affinity DataIC50: 961nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant human HDAC10 (2 to 631 residues) expressed in baculovirus sf9 insect cells expression system using B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50647413(CHEMBL5597560)
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of recombinant human full length HDAC2 using Boc-Lys (Ac)-AMC as substrate incubated for 120 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50647413(CHEMBL5597560)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human full length HDAC11 using Boc-Lys (Tfa)-AMC as substrate incubated for 120 mins by fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed