BDBM50647581 CHEMBL5597522

SMILES COC(=O)[C@H](Cc1cnc[nH]1)NC(=O)Cc1cccc(O[C@H]2CCc3cc(-c4cncc(Oc5ccccc5)c4)ccc32)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50647581   

TargetGDNF family receptor alpha-3(Homo sapiens)
Cerevel Therapeutics

Curated by ChEMBL
LigandPNGBDBM50647581(CHEMBL5597522)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of GFRalpha3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGDNF family receptor alpha-1(Homo sapiens)
Cerevel Therapeutics

Curated by ChEMBL
LigandPNGBDBM50647581(CHEMBL5597522)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GFRalpha1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGDNF family receptor alpha-2(Homo sapiens)
Cerevel Therapeutics

Curated by ChEMBL
LigandPNGBDBM50647581(CHEMBL5597522)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GFRalpha2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Cerevel Therapeutics

Curated by ChEMBL
LigandPNGBDBM50647581(CHEMBL5597522)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed