BDBM50647588 CHEMBL5596637

SMILES CNC(=O)[C@H](NC(=O)Cc1cccc(O[C@H]2CCc3cc(-c4cnc(Nc5cncnc5)nc4)ccc32)c1)C1CCCCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50647588   

TargetGDNF family receptor alpha-1(Homo sapiens)
Cerevel Therapeutics

Curated by ChEMBL
LigandPNGBDBM50647588(CHEMBL5596637)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GFRalpha1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGDNF family receptor alpha-2(Homo sapiens)
Cerevel Therapeutics

Curated by ChEMBL
LigandPNGBDBM50647588(CHEMBL5596637)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GFRalpha2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGDNF family receptor alpha-3(Homo sapiens)
Cerevel Therapeutics

Curated by ChEMBL
LigandPNGBDBM50647588(CHEMBL5596637)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GFRalpha3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Cerevel Therapeutics

Curated by ChEMBL
LigandPNGBDBM50647588(CHEMBL5596637)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed