BDBM50647640 CHEMBL5597854

SMILES CCc1nc(N)nc(N)c1OCCCCOc1ccc(-c2ccccc2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50647640   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium Falciparum)
National Center for Genetic Engineering and Biotechnology (BIOTEC)

Curated by ChEMBL
LigandPNGBDBM50647640(CHEMBL5597854)
Affinity DataKi:  0.260nMAssay Description:Inhibition of wild type Plasmodium falciparum DHFR expressed in Escherichia coli BL21(DE3) pLysS cells assessed as inhibition constant using DHF as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDihydrofolate reductase(Human)
National Center for Genetic Engineering and Biotechnology (BIOTEC)

Curated by ChEMBL
LigandPNGBDBM50647640(CHEMBL5597854)
Affinity DataKi:  13nMAssay Description:Inhibition of human DHFR expressed in Escherichia coli BL21(DE3) pLysS cells assessed as inhibition constant using DHF as substrate measured for 80 s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed