BDBM50647814 CHEMBL5591124

SMILES CN1CCN(c2ccc(Nc3ncc(Cl)c(Nc4ccccc4P(C)(C)=O)n3)cc2Br)CC1

InChI Key InChIKey=ZRTULLUVVJRZKH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50647814   

TargetEpidermal growth factor receptor(Human)
R. C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647814BDBM50647814(CHEMBL5591124)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant EGFR-del19/T790M/C797S triple mutant extracted from Sf9 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
R. C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647814BDBM50647814(CHEMBL5591124)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of EGFR Del19/T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
R. C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647814BDBM50647814(CHEMBL5591124)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of C-terminal His-tagged/N-terminal GST-tagged human recombinant EGFR T790M/C797S/L858R triple mutant (668 to 1210 residues) extracted fro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed