BDBM50647911 CHEMBL5596626

SMILES Cn1c(=O)n(C(C)(C)C#N)c2c3cc(-c4cnc5ccccc5c4)ccc3ncc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50647911   

LigandPNGBDBM50647911(CHEMBL5596626)
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50647911(CHEMBL5596626)
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50647911(CHEMBL5596626)
Affinity DataIC50: 5nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50647911(CHEMBL5596626)
Affinity DataIC50: 7nMAssay Description:Inhibition of ATM (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50647911(CHEMBL5596626)
Affinity DataIC50: 7nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50647911(CHEMBL5596626)
Affinity DataIC50: 20nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-1-antitrypsin-related protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50647911(CHEMBL5596626)
Affinity DataIC50: 20nMAssay Description:Inhibition of ATR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50647911(CHEMBL5596626)
Affinity DataIC50: 75nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate measured for 1 hr by ADP-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed