BDBM50647953 CHEMBL5596579

SMILES COc1cc(-c2ccn3nc(N)c(-c4cnn(C(F)F)c4)c3n2)cnc1OC

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50647953   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50647953(CHEMBL5596579)Copy SMILES

Affinity DataIC50: 3.70nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PI3:PS as substrate incubated for 1 hr in presence of ATP by ADP-glo kinase assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50647953(CHEMBL5596579)Copy SMILES

Affinity DataIC50: 4.30nMAssay Description:Inhibition of PI3K alpha (unknown origin) using PI3:PS as substrate incubated for 1 hr in presence of ATP by ADP-glo kinase assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50647953(CHEMBL5596579)Copy SMILES

Affinity DataIC50: 5.10nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PI3:PS as substrate incubated for 1 hr in presence of ATP by ADP-glo kinase assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL