BDBM50648020 CHEMBL5597266

SMILES N#CC1(CNc2cccc(-c3cc(Nc4cnn(Cc5ccc(C(=O)Nc6ccccc6N)cc5)c4)ncc3Cl)n2)CCOCC1

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50648020   

TargetCyclin-dependent kinase 9(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 88nMAssay Description:Inhibition of CDK9 (unknown origin) using ULight 4EBP1 peptide as substrate incubated for 2 hrs in presence of ATP by FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetHistone deacetylase 1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 169nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Lys-Tyr-Lys(eta-acetyl)-AMC as substrate incubated for 24 hrs by fluorescence based Envision plate rea...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetHistone deacetylase 3(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of human recombinant HDAC3 using Ac-Lys-Tyr-Lys(eta-acetyl)-AMC as substrate incubated for 24 hrs by fluorescence based Envision plate rea...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetCyclin-dependent kinase 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2 (unknown origin) using ULight 4EBP1 peptide as substrate incubated for 2 hrs in presence of ATP by FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetInterleukin-1 receptor-associated kinase 4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetSerine/threonine-protein kinase Chk1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetCyclin-dependent kinase 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetSerine/threonine-protein kinase pim-1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetSerine/threonine-protein kinase 17B(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DRAK2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetEpidermal growth factor receptor(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetAurora kinase A(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AurorA (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of P70S6K (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetHistone deacetylase 4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC4 using Ac-Leu-Gly-Lys(Tfa)-AMC as substrate incubated for 24 hrs by fluorescence based Envision plate reader ana...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
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TargetHistone deacetylase 6(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50648020(CHEMBL5597266)Copy SMILES

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC6 using Boc-Lys(eta-acetyl)-AMC as substrate incubated for 24 hrs by fluorescence based Envision plate reader ana...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/12/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL