BDBM50648048 CHEMBL5598430

SMILES Cn1c(=O)c2c(nc(S(C)(=O)=O)n2C)n(CC#Cc2cccc(NC(=O)CN3CCN(c4ccc5c(c4)C(=O)N(C4CCC(=O)NC4=O)C5=O)CC3)c2)c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50648048   

TargetMatrix metalloproteinase-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50648048(CHEMBL5598430)
Affinity DataIC50: 5.31E+3nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInterstitial collagenase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50648048(CHEMBL5598430)
Affinity DataIC50: 8.69E+3nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBeta-secretase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50648048(CHEMBL5598430)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BACE-1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCathepsin B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50648048(CHEMBL5598430)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Cathepsin BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50648048(CHEMBL5598430)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDE4B1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50648048(CHEMBL5598430)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDE1AMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50648048(CHEMBL5598430)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Factor XaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCoagulation factor VII(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50648048(CHEMBL5598430)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Factor VIIaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCathepsin D(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50648048(CHEMBL5598430)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Cathepsin DMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50648048(CHEMBL5598430)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCaspase-8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50648048(CHEMBL5598430)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human caspase-8More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50648048(CHEMBL5598430)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human caspase-3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed