BDBM50648143 CHEMBL5596442

SMILES C#Cc1nn(-c2cc(Cl)c(Oc3cc(C(C)C)c(=O)[nH]n3)c(Cl)c2)c(=O)[nH]c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50648143   

TargetThyroid hormone receptor beta(Human)
Aligos Belgium BV

Curated by ChEMBL
LigandPNGBDBM50648143(CHEMBL5596442)
Affinity DataEC50:  19nMAssay Description:Agonist activity at full length GST-tagged human THR-beta LBD incubated for 1 hr in presence of fluorescein labeled SRC2-2 peptide by Lanthascreen TR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Aligos Belgium BV

Curated by ChEMBL
LigandPNGBDBM50648143(CHEMBL5596442)
Affinity DataEC50:  54nMAssay Description:Agonist activity at THR-beta in HEK293T cells incubated for 18 to 24 hrs by EnSpire plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Aligos Belgium BV

Curated by ChEMBL
LigandPNGBDBM50648143(CHEMBL5596442)
Affinity DataEC50:  79nMAssay Description:Agonist activity at full length GST-tagged human THR-alpha LBD incubated for 1 hr in presence of fluorescein labeled SRC2-2 peptide by Lanthascreen T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetThyroid hormone receptor alpha(Human)
Aligos Belgium BV

Curated by ChEMBL
LigandPNGBDBM50648143(CHEMBL5596442)
Affinity DataEC50:  175nMAssay Description:Agonist activity at THR-alpha in HEK293T cells incubated for 18 to 24 hrs by EnSpire plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed