BDBM50648485 CHEMBL5614363

SMILES CCCCN(CCc1c(C)[nH]c2ccccc12)Cc1ccc(/C=C/C(=O)NNCCC)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50648485   

TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 1.40nMAssay Description:Time dependent inhibition of recombinant human HDAC3 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated for 120 min followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 2.70nMAssay Description:Time dependent inhibition of recombinant human HDAC3 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated for 90 min followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 4nMAssay Description:Time dependent inhibition of recombinant human HDAC3 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated for 60 min followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated for 1 hr followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 9.30nMAssay Description:Time dependent inhibition of recombinant human HDAC3 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated for 30 min followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 19nMAssay Description:Time dependent inhibition of recombinant human HDAC3 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated for 15 min followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 57nMAssay Description:Time dependent inhibition of recombinant human HDAC3 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated with compound followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 151nMAssay Description:Time dependent inhibition of recombinant human HDAC1 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated for 120 min followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 202nMAssay Description:Time dependent inhibition of recombinant human HDAC1 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated for 90 min followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 252nMAssay Description:Time dependent inhibition of recombinant human HDAC1 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated for 30 min followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 286nMAssay Description:Time dependent inhibition of recombinant human HDAC1 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated for 60 min followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 298nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated for 1 hr followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 464nMAssay Description:Time dependent inhibition of recombinant human HDAC1 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated for 15 min followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 879nMAssay Description:Time dependent inhibition of recombinant human HDAC1 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated with compound followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-Lys (acetyl)-AMC as flurogenic substrate preincubated for 1 hr followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 5.57E+3nMAssay Description:Inhibition of human recombinant HDAC11 preincubated for 1 hr followed by substrate addition and measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC9 preincubated for 1 hr followed by substrate addition and measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC7 preincubated for 1 hr followed by substrate addition and measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC6 preincubated for 1 hr followed by substrate addition and measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC5 preincubated for 1 hr followed by substrate addition and measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC8 preincubated for 1 hr followed by substrate addition and measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50648485(CHEMBL5614363)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC4 preincubated for 1 hr followed by substrate addition and measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed