BDBM50648517 CHEMBL5612303

SMILES NC(=O)c1cc2ncnc(N3[C@@H]4CC[C@H]3CN(C(=O)Nc3ccc(C(F)(F)F)cc3)C4)c2s1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50648517   

LigandPNGBDBM50648517(CHEMBL5612303)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human SIRT3 using Fluor de lys as substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Shihezi University

Curated by ChEMBL
LigandPNGBDBM50648517(CHEMBL5612303)
Affinity DataIC50: 387nMAssay Description:Inhibition of N-terminal recombinant his-tagged human SIRT1 expressed in Escherichia coli using Fluor de lys as substrate incubated for 30 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Shihezi University

Curated by ChEMBL
LigandPNGBDBM50648517(CHEMBL5612303)
Affinity DataIC50: 474nMAssay Description:Inhibition of recombinant human SIRT2 using Fluor de lys as substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed