BDBM50648614 CHEMBL5612129

SMILES CCOC(=O)c1c(Br)c2c(n1Cc1cccc(C)c1)-c1[nH]c(=O)c(S(=O)(=O)c3ccccc3)cc1CC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50648614   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50648614(CHEMBL5612129)
Affinity DataEC50:  450nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing halide-sensitive yellow fluorescent protei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCystic fibrosis transmembrane conductance regulator(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50648614(CHEMBL5612129)
Affinity DataEC50:  750nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing halide-sensitive yellow fluorescent protei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed