BDBM50648726 CHEMBL5612392

SMILES O=C(NO)c1ccc(S(=O)(=O)n2ccc3cc(OCCCN4CCCCC4)ccc32)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50648726   

TargetHistone deacetylase 6(Human)
Institute of General Organic Chemistry (CSIC)

Curated by ChEMBL
LigandPNGBDBM50648726(CHEMBL5612392)
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST tagged full length human recombinant HDAC6 (1 to 1215 residues) extracted from Sf9 cells using Z-Lys(Ac)-AMC as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute of General Organic Chemistry (CSIC)

Curated by ChEMBL
LigandPNGBDBM50648726(CHEMBL5612392)
Affinity DataIC50: 735nMAssay Description:Inhibition of C-terminal 6His/FLAG tagged full length human recombinant HDAC1 (1 to 482 residues) extracted from Sf9 cells using Z-Lys(Ac)-AMC as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Institute of General Organic Chemistry (CSIC)

Curated by ChEMBL
LigandPNGBDBM50648726(CHEMBL5612392)
Affinity DataIC50: 937nMAssay Description:Inhibition of human recombinant C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GDT tagged human NCOR2 (395 to 489 residues) extracted fro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Institute of General Organic Chemistry (CSIC)

Curated by ChEMBL
LigandPNGBDBM50648726(CHEMBL5612392)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of C-terminal FLAG-tagged full length human recombinant HDAC2 (1 to 488 residues) extracted from Sf9 cells using Z-Lys(Ac)-AMC as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Institute of General Organic Chemistry (CSIC)

Curated by ChEMBL
LigandPNGBDBM50648726(CHEMBL5612392)
Affinity DataKi:  3.39E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor extracted from CHO-K1 cell membrane assessed as inhibition constant incubated for 1 hr by Microbet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed