BDBM50648873 CHEMBL5613885

SMILES C=CC(=O)N(c1ccc(O[C@@H]2CC[C@@H](N)C2)cc1)[C@H](C)c1ccc(C(F)(F)F)c(C#N)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50648873   

TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50648873(CHEMBL5613885)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Bfl-1 (1 to 151 residues)(unknown origin) extracted from Escherichia coli BL21-Gold (DE3) using HyLi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50648873(CHEMBL5613885)
Affinity DataEC50:  6.90E+3nMAssay Description:Inhibition of Bfl-1 in human SU-DHL-1 cells assessed as caspase-3/7 activation measured after 6 hrs by UPLC-MRM MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed