BDBM50648950 CHEMBL5613744

SMILES N=C(N)NCCC[C@H](N)C(=O)NCC(=O)N[C@@H](CCCN)C(=O)N[C@@H](CCCNC(=N)NCCCSC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)C(=O)O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50648950   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50648950(CHEMBL5613744)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of human PRMT5/MEP50 using Histone H2 as substrate and SAM as cofactor by radiometric HotSpot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50648950(CHEMBL5613744)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human PRMT4 using histone H3 as substrate and SAM as cofactor by radiometric HotSpot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50648950(CHEMBL5613744)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human PRMT1 using Histone H4 as substrate and SAM as cofactor by radiometric HotSpot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50648950(CHEMBL5613744)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human PRMT7 using GST-GAR as substrate and SAM as cofactor by radiometric HotSpot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 3(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50648950(CHEMBL5613744)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PRMT3 using Histone H3 as substrate and SAM as cofactor by radiometric HotSpot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50648950(CHEMBL5613744)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PRMT8 using Histone H4 as substrate and SAM as cofactor by radiometric HotSpot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed