BDBM50649179 CHEMBL5619189

SMILES C[C@H](CCC(=O)N[C@H](CC(=O)O)Cc1cn(S(=O)(=O)c2ccc(C(F)(F)F)cc2)c2ccccc12)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50649179   

TargetEphrin type-A receptor 2(Mouse)
Universita di Parma

Curated by ChEMBL
LigandPNGBDBM50649179(CHEMBL5619189)
Affinity DataIC50: 2.60E+3nMAssay Description:Displacement of biotinylated Fc-tagged ephrin-A1 from C/N-terminal 6-His tagged mouse recombinant EphA2 (Ala22 to Ala535 residues) preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-A receptor 2(Mouse)
Universita di Parma

Curated by ChEMBL
LigandPNGBDBM50649179(CHEMBL5619189)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of biotinylated Fc-tagged ephrin-A1 from C/N-terminal 6-His tag mouse recombinant EphA2 (Ala22 to Ala535 residues) assessed as inhibitio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-A receptor 4(Mouse)
Universita di Parma

Curated by ChEMBL
LigandPNGBDBM50649179(CHEMBL5619189)
Affinity DataIC50: 4.20E+3nMAssay Description:Displacement of biotinylated Fc-tagged ephrin-A1 from recombinant N/C-terminal 6-his tagged mouse EphA4 (Val20 to Thr547 residues) preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-A receptor 3(Mouse)
Universita di Parma

Curated by ChEMBL
LigandPNGBDBM50649179(CHEMBL5619189)
Affinity DataIC50: 7.60E+3nMAssay Description:Displacement of biotinylated Fc-tagged ephrin-A1 from recombinant N/C-terminal 6-his tagged mouse EphA3 (Glu21 to His541 residues) preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-A receptor 5(Rat)
Universita di Parma

Curated by ChEMBL
LigandPNGBDBM50649179(CHEMBL5619189)
Affinity DataIC50: 9.30E+3nMAssay Description:Displacement of biotinylated Fc-tagged ephrin-A1 from recombinant N/C-terminal 6-his tagged rat EphA5 (Ser 58 to Gln573 residues) preincubated for 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-A receptor 6(Mouse)
Universita di Parma

Curated by ChEMBL
LigandPNGBDBM50649179(CHEMBL5619189)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of biotinylated Fc-tagged ephrin-A1 from recombinant N/C-terminal 6-his tagged mouse EphA6 (Ser28 to Gln546 residues) preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-A receptor 1(Human)
Universita di Parma

Curated by ChEMBL
LigandPNGBDBM50649179(CHEMBL5619189)
Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of biotinylated Fc-tagged ephrin-A1 from N/C-terminal 6-his tagged human recombinant EphA1 (Lys26 to Glu547 residues) preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-A receptor 8(Mouse)
Universita di Parma

Curated by ChEMBL
LigandPNGBDBM50649179(CHEMBL5619189)
Affinity DataIC50: 1.30E+4nMAssay Description:Displacement of biotinylated Fc-tagged ephrin-A1 from recombinant N/C-terminal 6-his tagged mouse EphA8 (Gly27 to Arg540 residues) preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-A receptor 7(Mouse)
Universita di Parma

Curated by ChEMBL
LigandPNGBDBM50649179(CHEMBL5619189)
Affinity DataIC50: 1.50E+4nMAssay Description:Displacement of biotinylated Fc-tagged ephrin-A1 from recombinant N/C-terminal 6-his tagged mouse EphA7 (Ala30 to Pro549 residues) preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-B receptor 2(Mouse)
Universita di Parma

Curated by ChEMBL
LigandPNGBDBM50649179(CHEMBL5619189)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of biotinylated Fc-tagged ephrin-B1 from recombinant N/C-terminal 6-his tagged mouse EphB2 (Val27 to Lys548 residues) preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-B receptor 1(Rat)
Universita di Parma

Curated by ChEMBL
LigandPNGBDBM50649179(CHEMBL5619189)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of biotinylated Fc-tagged ephrin-B1 from N/C-terminal recombinant rat EphB1 (Met18 to Gln538 residues) preincubated for 1 hr followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-B receptor 3(Mouse)
Universita di Parma

Curated by ChEMBL
LigandPNGBDBM50649179(CHEMBL5619189)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of biotinylated Fc-tagged ephrin-B1 from recombinant mouse EphB3 (Leu 30 to Thru537 residues) preincubated for 1 hr followed by ephrin-B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed