BDBM50649359 CHEMBL5620138

SMILES COc1cc(-n2ncc3c(-c4cccc(-c5nc6cc(CN(C)[C@H]7CC[C@H](C(=O)O)CC7)cc(C#N)c6o5)c4C)cccc32)cc(OC)c1CN(C)[C@@H]1CCOC[C@@H]1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50649359   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50649359(CHEMBL5620138)
Affinity DataEC50:  15nMAssay Description:Inhibition of interaction of human PD-1 expressed in human Jurkat T cells co-expressing Luc/human PD-L1 expressed in CHO-K1 cells assessed as activat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50649359(CHEMBL5620138)
Affinity DataIC50: 19nMAssay Description:Induction of internalization of PD-L1 (unknown origin) expressed in CHO-K1 cells assessed as reduction in surface PD-L1 expression incubated for 16 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50649359(CHEMBL5620138)
Affinity DataIC50: 46nMAssay Description:Induction of PD-L1 internalization in human whole blood incubated for 24 hrs by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProgrammed cell death protein 1(Mouse)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50649359(CHEMBL5620138)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse PD-1/PD-L1 interactionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed