BDBM50649391 CHEMBL5618854

SMILES COc1ccc(-n2ccc3c(=O)n(CC4(O)CCN(C(=O)C[C@@H](C)c5ccccc5)CC4)cnc32)cc1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50649391   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50649391(CHEMBL5618854)
Affinity DataIC50: 42nMAssay Description:Inhibition of USP7 (unknown origin) using Ub-AFC as substrate assessed as substrate cleavage preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50649391(CHEMBL5618854)
Affinity DataKd:  156nMAssay Description:Binding affinity to USP7 (unknown origin) assessed as dissociation constant by fluorescence based thermal shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed