BDBM50649405 CHEMBL5618982

SMILES COc1cc(-c2ccnc(Nc3cccc(N(C)C)c3)n2)ccc1O

InChI Key

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50649405   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50649405(CHEMBL5618982)
Affinity DataIC50: 22nMAssay Description:Inhibition of human FLT3 (unknown origin) using poly(Glu,Tyr) as substrate incubated for 2 hrs in presence of ATP by luminescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50649405(CHEMBL5618982)
Affinity DataIC50: 23nMAssay Description:Inhibition of N-terminal human recombinant JAK2 using poly(Glu,Ala,Tyr) as substrate incubated for 2 hrs in presence of ATP by luminescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed