BDBM50649449 CHEMBL5619410

SMILES NC[C@@H](C(=O)Nc1ccc2cnccc2c1)c1ccc(COC(=O)c2cccc(CO[N+](=O)[O-])c2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50649449   

TargetRho-associated protein kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50649449(CHEMBL5619410)
Affinity DataIC50: 0.660nMAssay Description:Inhibition of ROCK2 (unknown origin) incubated for 60 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50649449(CHEMBL5619410)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ROCK1 (unknown origin) incubated for 10 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed