BDBM50649520 CHEMBL5618445::US20250257059, Example 110

SMILES CC[C@@H]1CCN(CCc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50649520   

TargetReceptor-type tyrosine-protein phosphatase N2 [1-387](Homo sapiens (Human))
Nerio Therapeutics

US Patent
LigandPNGBDBM50649520(CHEMBL5618445 | US20250257059, Example 110)
Affinity DataIC50: 2nMAssay Description:PTPN2 was produced in E. coli as a GST-TEV fusion and the GST was removed by TEV digestion, followed by additional purification to yield full-length ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50649520(CHEMBL5618445 | US20250257059, Example 110)
Affinity DataIC50: 2nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed