BDBM50649522 CHEMBL5618189::US20250313554, Compound 3

SMILES CC1CCN=C(Nc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2)N1

InChI Key InChIKey=ZQCMFHAFPWWDAP-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50649522   

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649522BDBM50649522(CHEMBL5618189 | US20250313554, Compound 3)
Affinity DataKi:  5nMAssay Description:Binding affinity to PTPN2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649522BDBM50649522(CHEMBL5618189 | US20250313554, Compound 3)
Affinity DataIC50: 10nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Ness Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 50649522BDBM50649522(CHEMBL5618189 | US20250313554, Compound 3)
Affinity DataKi:  30nMAssay Description:Compound activity was determined using GST-tagged PTPN2 protein (Cat #31592, ActiveMotif) (SEQ ID NO: 1) in an in vitro enzymatic reaction. The enzym...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent