BDBM50649615 CHEMBL5618909

SMILES Cc1cc(-c2cc(NC(=O)Cc3ccccc3Cl)cc(C(F)(F)F)c2)ccn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50649615   

TargetNuclear receptor subfamily 2 group E member 1(Human)
Ludwig-Maximilians-Universitat (LMU) Munchen

Curated by ChEMBL
LigandPNGBDBM50649615(CHEMBL5618909)
Affinity DataKd:  60nMAssay Description:Binding affinity to human TLX LBD assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 2 group E member 1(Human)
Ludwig-Maximilians-Universitat (LMU) Munchen

Curated by ChEMBL
LigandPNGBDBM50649615(CHEMBL5618909)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human TLX LBD expressed in HEK293T cells co-transfected with RL/Gal4-VP16 assessed as repression of VP16-induced reporter activit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor ROR-alpha(Human)
Ludwig-Maximilians-Universitat (LMU) Munchen

Curated by ChEMBL
LigandPNGBDBM50649615(CHEMBL5618909)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of ROR-alpha (unknown origin) expressed in HEK293T cells co-transfected with RL/Gal4-VP16 incubated for 16 hrs by Dual-Glo Luciferase assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed