BDBM50649685 CHEMBL5618646

SMILES O=C1CCC(N2Cc3cc(C4=C[C@@]4(C(=O)OCC(Cl)(Cl)Cl)c4ccc(Br)cc4)ccc3C2=O)C(=O)N1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50649685   

TargetSal-like protein 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50649685(CHEMBL5618646)
Affinity DataEC50:  75nMAssay Description:Induction of C-terminal HiBiT tag knocked in SALL4 degradation in human NCCIT cells incubated for 60 mins by Nano-Glo HiBiT lytic reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCasein kinase I isoform alpha(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50649685(CHEMBL5618646)
Affinity DataEC50:  250nMAssay Description:Induction of ePL tagged CK1alpha degradation in human MDS-L cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50649685(CHEMBL5618646)
Affinity DataEC50:  3.30E+3nMAssay Description:Induction of ePL tagged GSPT1 degradation in human DF15 cells incubated for 60 mins by luminescence reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetZinc finger protein Aiolos(Homo sapiens)
Emory University

Curated by ChEMBL
LigandPNGBDBM50649685(CHEMBL5618646)
Affinity DataEC50:  4.80E+3nMAssay Description:Induction of N-terminal HiBiT tag knocked in IKZF3 degradation in human DF15 cells incubated for 60 mins by Nano-Glo HiBiT lytic reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed