BDBM50649866 CHEMBL5630913

SMILES Cc1cc(N2CCN(C(c3ccccc3)c3ccccc3)CC2)nc2ccc(Cl)cc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50649866   

TargetEpidermal growth factor receptor(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50649866(CHEMBL5630913)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of wild type EGFR (unknown origin) by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50649866(CHEMBL5630913)
Affinity DataIC50: 136nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin) using TK-substrate preincubated with enzyme for 30 mins followed by substrate for 10 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed