BDBM50649920 CHEMBL5631080

SMILES CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ncc(S(=O)(=O)c5cccc(F)c5)cc34)cc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50649920   

TargetALK tyrosine kinase receptor(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50649920(CHEMBL5631080)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of wild-type ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50649920(CHEMBL5631080)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50649920(CHEMBL5631080)
Affinity DataIC50: 1nMAssay Description:Inhibition of ROS1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed