BDBM50649924 CHEMBL5630153

SMILES C[C@H]1Nc2ccn3ncc(c3n2)C(=O)N[C@@]2(C)CC3=CC(F)=CC1C3O2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50649924   

LigandPNGBDBM50649924(CHEMBL5630153)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of recombinant human ROS1 G2032R mutant preincubated for 5 to 10 mins followed by substrate and ATP addition and measured after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649924(CHEMBL5630153)
Affinity DataIC50: 0.840nMAssay Description:Inhibition of recombinant human ROS1 preincubated for 5 to 10 mins followed by substrate and ATP addition and measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649924(CHEMBL5630153)
Affinity DataIC50: 2nMAssay Description:Inhibition of human ALK preincubated for 5 to 10 mins followed by substrate and ATP addition and measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649924(CHEMBL5630153)
Affinity DataIC50: 21nMAssay Description:Inhibition of human ALK L1196M/G1202R double mutant preincubated for 5 to 10 mins followed by substrate and ATP addition and measured after 60 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed