BDBM50649925 CHEMBL5624610::US12435089, Example 10

SMILES COc1ccc(F)cc1[C@@H](C)Nc1ccn2ncc(C3=NOC(C)(C)N3)c2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50649925   

LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human ROS1 G2032R mutant using KKKSPGEYVNIEFG as substrate incubated for 120 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human ROS1 using KKKSPGEYVNIEFG as substrate incubated for 120 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details US Patent

LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details US Patent

LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details US Patent

LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 0.5nMAssay Description:Serial dilutions of the compound were prepared with 10% DMSO, and 5 μl of each dilution was added to a 50 μl reaction vessel to result in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details US Patent

LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details US Patent

LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 2.75nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details US Patent

LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 2.75nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details US Patent

LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 2.75nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details US Patent

LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 27.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details US Patent

TargetTGF-beta receptor type-1(Human)TBA
LigandPNGBDBM50649925(CHEMBL5624610 | US12435089, Example 10)
Affinity DataIC50: 50nMAssay Description:Inhibition of human ALK5 using Casein as substrate incubated for 120 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed