BDBM50649926 CHEMBL5625106

SMILES CCOc1ccc(F)cc1[C@@H](C)Nc1ccn2ncc(C3=NOC(C)N3)c2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50649926   

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50649926(CHEMBL5625106)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human ROS1 using KKKSPGEYVNIEFG as substrate incubated for 120 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50649926(CHEMBL5625106)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human ROS1 G2032R mutant using KKKSPGEYVNIEFG as substrate incubated for 120 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50649926(CHEMBL5625106)
Affinity DataIC50: 50nMAssay Description:Inhibition of human ALK5 using Casein as substrate incubated for 120 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed