BDBM50650139 CHEMBL5631203

SMILES N[C@H]1CC[C@H](Oc2ccncc2NC(=O)c2csc(-c3c(F)cccc3F)n2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50650139   

TargetSerine/threonine-protein kinase pim-1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50650139(CHEMBL5631203)
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type full length N-terminal his-tagged PIM1 (1 to 313 residues) (unknown origin) expressed in Sf21 insect cells using STK3 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50650139(CHEMBL5631203)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of wild type N-terminal GST-tagged PIM3 (1 to 326 residues) (unknown origin) expressed in Sf21 insect cells using STK3 as substrate incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50650139(CHEMBL5631203)
Affinity DataIC50: 39nMAssay Description:Inhibition of N-terminal GST-tagged PIM2 (1 to 311 residues) (unknown origin) expressed in Sf21 insect cells using STK3 as substrate incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed