BDBM50650142 CHEMBL5630386

SMILES O=C(Nc1cnccc1OC1CC2CCC(C1)N2)c1csc(-c2c(F)cccc2F)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50650142   

TargetSerine/threonine-protein kinase pim-1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50650142(CHEMBL5630386)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of wild type full length N-terminal his-tagged PIM1 (1 to 313 residues) (unknown origin) expressed in Sf21 insect cells using STK3 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50650142(CHEMBL5630386)
Affinity DataIC50: 15nMAssay Description:Inhibition of wild type N-terminal GST-tagged PIM3 (1 to 326 residues) (unknown origin) expressed in Sf21 insect cells using STK3 as substrate incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50650142(CHEMBL5630386)
Affinity DataIC50: 141nMAssay Description:Inhibition of N-terminal GST-tagged PIM2 (1 to 311 residues) (unknown origin) expressed in Sf21 insect cells using STK3 as substrate incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed