BDBM50650221 CHEMBL5630048

SMILES O=S(=O)(Nc1cc(-c2cnc3[nH]nc(-c4ccc(N5CCCCC5)nc4)c3c2)cnc1Cl)c1ccccc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50650221   

LigandPNGBDBM50650221(CHEMBL5630048)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate incubated for 60 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50650221(CHEMBL5630048)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant human mTOR (1362 to end residues) using ULight-4E-BP1 (Thr37/46) peptide as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed