BDBM50650332 CHEMBL5630341

SMILES CC1(N)CCN(c2nnc(Sc3ccc4ccccc4c3)s2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50650332   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650332(CHEMBL5630341)
Affinity DataIC50: 720nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650332(CHEMBL5630341)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of full length wild type recombinant human SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650332(CHEMBL5630341)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human SHP2 PTPase activity (219 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650332(CHEMBL5630341)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length recombinant human SHP1 (1 to 570 residues) using DIPMUP as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed