BDBM50650336 CHEMBL5630569

SMILES C[C@@H]1OCC2(CCN(c3nnc(Sc4cccc(Cl)c4Cl)s3)CC2)[C@@H]1N

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50650336   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650336(CHEMBL5630569)
Affinity DataIC50: 250nMAssay Description:Inhibition of full length wild type recombinant human IRS-1 peptide activated SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650336(CHEMBL5630569)
Affinity DataIC50: 840nMAssay Description:Inhibition of full length wild type recombinant human SHP2 (1 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650336(CHEMBL5630569)
Affinity DataIC50: 6.88E+3nMAssay Description:Inhibition of full length recombinant human SHP2 E76K mutant (1 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650336(CHEMBL5630569)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human SHP2 PTPase activity (219 to 525 residues) using DIPMUP as substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Affiliated Hospital of Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50650336(CHEMBL5630569)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length recombinant human SHP1 (1 to 570 residues) using DIPMUP as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed