BDBM50650415 CHEMBL5630869

SMILES COc1cc(-c2nc(C(=O)NCc3ccc(C(=O)NO)cc3)cc3c2[nH]c2ccccc23)cc(OC)c1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50650415   

TargetHistone deacetylase 6(Human)
Shanghai Institute of Pharmaceutical Industry Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50650415(CHEMBL5630869)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of N-terminal FLAG-tagged full length human recombinant HDAC6 expressed in baculovirusMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Shanghai Institute of Pharmaceutical Industry Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50650415(CHEMBL5630869)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of C-terminal FLAG-tagged human recombinant HDAC1 expressed in baculovirus by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Shanghai Institute of Pharmaceutical Industry Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50650415(CHEMBL5630869)
Affinity DataIC50: 559nMAssay Description:Inhibition of C-terminal FLAG-tagged full length human recombinant HDAC8 expressed in baculovirusMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Shanghai Institute of Pharmaceutical Industry Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50650415(CHEMBL5630869)
Affinity DataIC50: 559nMAssay Description:Inhibition of C-terminal FLAG-tagged full length human recombinant HDAC2 expressed in Sf9 cells by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed