BDBM50650930 CHEMBL5633539

SMILES NC(=O)c1cccc2[nH]c(NC(=O)c3cccc(C(=O)N4CCC(Nc5ncc(I)cn5)CC4)c3)nc12

InChI Key InChIKey=VQUQBABVYFSBGV-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50650930   

TargetPoly [ADP-ribose] polymerase 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650930BDBM50650930(CHEMBL5633539)
Affinity DataIC50: 30nMAssay Description:Inhibition of PARP2 (unknown origin) incubated for 1 hr by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650930BDBM50650930(CHEMBL5633539)
Affinity DataIC50: 30nMAssay Description:Inhibition of human PARP2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650930BDBM50650930(CHEMBL5633539)
Affinity DataIC50: 34nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 1 hr by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650930BDBM50650930(CHEMBL5633539)
Affinity DataIC50: 34nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650930BDBM50650930(CHEMBL5633539)
Affinity DataIC50: 285nMAssay Description:Inhibition of CDK12 (unknown origin) in presence of ATP by kinase-glo plus luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650930BDBM50650930(CHEMBL5633539)
Affinity DataIC50: 285nMAssay Description:Inhibition of human CDK12More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650930BDBM50650930(CHEMBL5633539)
Affinity DataIC50: 517nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650930BDBM50650930(CHEMBL5633539)
Affinity DataIC50: 689nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 5(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650930BDBM50650930(CHEMBL5633539)
Affinity DataIC50: 748nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed