BDBM50651278 CHEMBL5632743

SMILES Nc1nc2c(ncn2[C@@H]2O[C@@H]3COP(=O)(O)O[C@H]4C[C@H](n5cnc6c(N)ncnc65)O[C@@H]4/C=C/P(=O)(O)O[C@H]3[C@H]2F)c(=O)[nH]1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50651278   

TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50651278(CHEMBL5632743)
Affinity DataEC50:  290nMAssay Description:Agonist activity at STING G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50651278(CHEMBL5632743)
Affinity DataEC50:  350nMAssay Description:Agonist activity at STING R71H/G230A/R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50651278(CHEMBL5632743)
Affinity DataEC50:  700nMAssay Description:Agonist activity at STING R232 mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed by washo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50651278(CHEMBL5632743)
Affinity DataEC50:  4.15E+3nMAssay Description:Agonist activity at STING R293Q mutant (unknown origin) expressed in digitonin -permeabilized HEK293T cells preincubated for 30 mins followed by wash...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed