BDBM50651358 CHEMBL5633703

SMILES CNCCN1CC[C@H](NC(=O)c2ccc3c(Nc4ccc(CN)cc4)ncnc3c2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50651358   

TargetProtein arginine N-methyltransferase 1(Human)
CSIR-Indian Institute of Chemical Biology (IICB)

Curated by ChEMBL
LigandPNGBDBM50651358(CHEMBL5633703)
Affinity DataIC50: 460nMAssay Description:Displacement of 3H-SAM from PRMT1 (unknown origin) using biotinylated-histone H4 peptide as substrate incubated for 45 mins by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
CSIR-Indian Institute of Chemical Biology (IICB)

Curated by ChEMBL
LigandPNGBDBM50651358(CHEMBL5633703)
Affinity DataKd:  2.00E+4nMAssay Description:Binding affinity to PRMT4 (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
CSIR-Indian Institute of Chemical Biology (IICB)

Curated by ChEMBL
LigandPNGBDBM50651358(CHEMBL5633703)
Affinity DataIC50: 9.20E+4nMAssay Description:Displacement of 3H-SAM from human PRMT4 in presence of substrate by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
CSIR-Indian Institute of Chemical Biology (IICB)

Curated by ChEMBL
LigandPNGBDBM50651358(CHEMBL5633703)
Affinity DataIC50: 4.36E+5nMAssay Description:Displacement of 3H-SAM from human PRMT6 in presence of substrate by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
CSIR-Indian Institute of Chemical Biology (IICB)

Curated by ChEMBL
LigandPNGBDBM50651358(CHEMBL5633703)
Affinity DataIC50: 4.60E+5nMAssay Description:Displacement of 3H-SAM from human PRMT1 in presence of substrate by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 8(Human)
CSIR-Indian Institute of Chemical Biology (IICB)

Curated by ChEMBL
LigandPNGBDBM50651358(CHEMBL5633703)
Affinity DataIC50: 8.23E+5nMAssay Description:Displacement of 3H-SAM from human PRMT8 in presence of substrate by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 3(Human)
CSIR-Indian Institute of Chemical Biology (IICB)

Curated by ChEMBL
LigandPNGBDBM50651358(CHEMBL5633703)
Affinity DataIC50: 1.39E+6nMAssay Description:Displacement of 3H-SAM from human PRMT3 in presence of substrate by SPA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed