BDBM50651427 CHEMBL5631614

SMILES Nc1nc(Cl)c2ncn(Cc3ccc(-c4noc(C(F)(F)F)n4)cc3F)c2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50651427   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50651427(CHEMBL5631614)
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC class IIa in human LNCaP cells incubated for 1 hr by HDAC-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50651427(CHEMBL5631614)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant HDAC4 (unknown origin) using trifluoroacetyl lysine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50651427(CHEMBL5631614)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant HDAC7 (unknown origin) using trifluoroacetyl lysine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50651427(CHEMBL5631614)
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant HDAC9 (unknown origin) using trifluoroacetyl lysine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50651427(CHEMBL5631614)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant HDAC5 (unknown origin) using trifluoroacetyl lysine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50651427(CHEMBL5631614)
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using RHKK-Ac-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50651427(CHEMBL5631614)
Affinity DataIC50: 860nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin) using RHKK-Ac-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50651427(CHEMBL5631614)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant HDAC10 (unknown origin) using RHKK-Ac-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50651427(CHEMBL5631614)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) using RHKK-Ac-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50651427(CHEMBL5631614)
Affinity DataIC50: 3.88E+4nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using RHKK-Ac-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50651427(CHEMBL5631614)
Affinity DataIC50: 4.51E+4nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) using RHK-Ac-K-Ac-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50651427(CHEMBL5631614)
Affinity DataIC50: 9.87E+4nMAssay Description:Inhibition of recombinant HDAC11 (unknown origin) using trifluoroacetyl lysine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed