BDBM50651693 CHEMBL1353989

SMILES COc1ccc2nc(O)c(-c3noc(-c4ccccc4)n3)cc2c1

InChI Key InChIKey=BRKAIFLXINCNLS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50651693   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651693BDBM50651693(CHEMBL1353989)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of WRN (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651693BDBM50651693(CHEMBL1353989)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of WRN (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRecQ-like DNA helicase BLM(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50651693BDBM50651693(CHEMBL1353989)
Affinity DataIC50: 4.61E+4nMAssay Description:Inhibition of BLM (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed