BDBM50651922 CHEMBL5639965

SMILES CCCNNC(=O)c1ccc(CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)Cc2ccccc2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50651922   

TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50651922(CHEMBL5639965)
Affinity DataIC50: 20nMAssay Description:Inhibition of human HDAC3 using Boc-Lys (acetyl)-AMC as substrate incubated for 1 hr followed by substrate addition and further incubated for 2 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50651922(CHEMBL5639965)
Affinity DataIC50: 30nMAssay Description:Inhibition of human HDAC1 using Boc-Lys (acetyl)-AMC as substrate incubated for 1 hr followed by substrate addition and further incubated for 2 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50651922(CHEMBL5639965)
Affinity DataIC50: 60nMAssay Description:Inhibition of human HDAC2 using Boc-Lys (acetyl)-AMC as substrate incubated for 1 hr followed by substrate addition and further incubated for 2 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAminopeptidase N(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50651922(CHEMBL5639965)
Affinity DataIC50: 340nMAssay Description:Inhibition of human CD13 using L-leucine-p-nitroanilide as substrate incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAminopeptidase N(Pig)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50651922(CHEMBL5639965)
Affinity DataIC50: 530nMAssay Description:Inhibition of porcine kidney CD13 using L-leucine-p-nitroanilide as substrate incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50651922(CHEMBL5639965)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of human HDAC11 using Boc-Lys (tri-fluoroacetyl)-AMC as substrate incubated for 1 hr followed by substrate addition and further incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50651922(CHEMBL5639965)
Affinity DataIC50: 4.65E+3nMAssay Description:Inhibition of human HDAC8 using Boc-Lys (tri-fluoroacetyl)-AMC as substrate incubated for 1 hr followed by substrate addition and further incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50651922(CHEMBL5639965)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HDAC4 using Boc-Lys (tri-fluoroacetyl)-AMC as substrate incubated for 1 hr followed by substrate addition and further incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50651922(CHEMBL5639965)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HDAC10 using Boc-Lys (tri-fluoroacetyl)-AMC as substrate incubated for 1 hr followed by substrate addition and further incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50651922(CHEMBL5639965)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HDAC6 using Boc-Lys (acetyl)-AMC as substrate incubated for 1 hr followed by substrate addition and further incubated for 2 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50651922(CHEMBL5639965)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HDAC5 using Boc-Lys (tri-fluoroacetyl)-AMC as substrate incubated for 1 hr followed by substrate addition and further incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50651922(CHEMBL5639965)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HDAC7 using Boc-Lys (tri-fluoroacetyl)-AMC as substrate incubated for 1 hr followed by substrate addition and further incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50651922(CHEMBL5639965)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HDAC9 using Boc-Lys (tri-fluoroacetyl)-AMC as substrate incubated for 1 hr followed by substrate addition and further incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed