BDBM50652204 CHEMBL5646626

SMILES CN1CCN(C2CCN(c3ccc(Nc4nc(Nc5ccccc5N(C)S(C)(=O)=O)c5cc[nH]c5n4)cc3F)CC2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50652204   

TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652204(CHEMBL5646626)
Affinity DataIC50: 4nMAssay Description:Inhibition of EGFR del19/T790M/C797S triple mutant (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652204(CHEMBL5646626)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50652204(CHEMBL5646626)
Affinity DataIC50: 4.58E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) in presence of ATP by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed