BDBM50652289 CHEMBL5639872

SMILES C=CC(=O)Nc1cc(F)ccc1-c1cc(C(=O)NCc2c(CCC)cc(C)[nH]c2=O)c(C)c(N(C)C2CCOCC2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50652289   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652289(CHEMBL5639872)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human N-terminal His-tagged EZH2 (2 to end residues) using [3H]-SAM as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652289(CHEMBL5639872)
Affinity DataIC50: 15nMAssay Description:Inhibition of EZH2 A677G mutant (unknown origin) using [3H]-SAM as substrate preincubated for 15 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed