BDBM50652379 CHEMBL5646721

SMILES COc1ccc(-c2cc(-c3ccc(Br)cc3)nc3[nH]nc(N)c23)cc1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50652379   

TargetAcetylcholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652379(CHEMBL5646721)
Affinity DataIC50: 160nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652379(CHEMBL5646721)
Affinity DataIC50: 260nMAssay Description:Inhibition of human GSK3beta by luminescent microplate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCholinesterase(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652379(CHEMBL5646721)
Affinity DataIC50: 690nMAssay Description:Inhibition of human BuChE measured after 15 to 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652379(CHEMBL5646721)
Affinity DataIC50: 770nMAssay Description:Inhibition of self mediated Amyloid beta (1 to 42) (unknown origin) aggregation measured every 5 mins by ThT fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50652379(CHEMBL5646721)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of human tau protein aggregation incubated for 1.5 hrs by TMB substrate based ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed