BDBM50652472 CHEMBL5646599

SMILES Cc1ccc(-c2ccnc3c(C#N)c(C)nn23)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50652472   

TargetActivin receptor type-1(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652472(CHEMBL5646599)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant GST-tagged-ALK2 (147 to 509 residues) using Casein as substrate in presence of ATP by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652472(CHEMBL5646599)
Affinity DataIC50: 134nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652472(CHEMBL5646599)
Affinity DataIC50: 3.08E+3nMAssay Description:Inhibition of human recombinant full-length PIM1 expressed in baculovirus infected Sf9 cells using S6K as substrate in presence of ATP by ADP-Glo lum...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed