BDBM50652513 CHEMBL5639135

SMILES COc1nc(-c2ccc(NC(=O)Nc3ccc(C(=O)NCCCCCC(=O)Nc4ccccc4N)cc3)cc2)nc(N2CCOCC2)n1

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50652513   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 20nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate incubated for 1 hrs in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 25nMAssay Description:Inhibition of HDAC3 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and measured after ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 30nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate incubated for 1 hrs in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 95nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate incubated for 1 hrs in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 206nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate incubated for 1 hrs in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 306nMAssay Description:Inhibition of HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and measured after ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 443nMAssay Description:Inhibition of HDAC2 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and measured after ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetHistone deacetylase 11(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC11 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and measured after...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetPolyamine deacetylase HDAC10(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC10 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and measured after...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetHistone deacetylase 9(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC9 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and measured after ...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetHistone deacetylase 8(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and measured after ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetHistone deacetylase 7(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and measured after ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and measured after ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetHistone deacetylase 5(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and measured after ...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
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TargetHistone deacetylase 4(Human)
Ocean University of China

Curated by ChEMBL

LigandBDBM50652513(CHEMBL5639135)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC4 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and measured after ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL