BDBM50652545 CHEMBL5647466

SMILES Cc1cc(C)c(CNC(=O)c2cc(-c3ccc4ncccc4c3)cc3[nH]c(=O)ccc23)c(=O)[nH]1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50652545   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50652545(CHEMBL5647466)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50652545(CHEMBL5647466)
Affinity DataIC50: 12nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed